| Rank | Value ($bil) | Acquired company | Host economya | Acquiring company | Home economya | Industry of the acquiring company |
| 1 | 52.2 | Anheuser-Busch Cos Inc | United States | InBev NV | Belgium | Malt beverages |
| 2 | 23.1 | Fortis Bank Nederland (Holding) NV | Belgium/Netherlands | Government of the Netherlands | Netherlands | National government |
| 3 | 17.9 | Altadis SA | Spain | Imperial Tobacco Overseas Holdings Ltd | United Kingdom | Investors, nec |
| 4 | 17.6 | Reuters Group PLC | United Kingdom | Thomson Corp | United States | Information retrieval services |
| 5 | 16.3 | Imperial Chemical Industries PLC | United Kingdom | Akzo Nobel NV | Netherlands | Paints, varnishes, lacquers, & allied products |
| 6 | 16.0 | Intelsat Ltd | Bermuda | Serafina Holdings Ltd | United Kingdom | Investors, nec |
| 7 | 15.0 | OCI Cement Group | Egypt | Lafarge SA | France | Cement, hydraulic |
| 8 | 14.9 | Scottish & Newcastle PLC | United Kingdom | Sunrise Acquisitions Ltd | Jersey | Investors, nec |
| 9 | 14.3 | Endesa Italia | Italy | E.ON AG | Germany | Electric services |
| 10 | 14.3 | Rio Tinto PLC | United Kingdom | Shining Prospect Pte Ltd | Singapore | Investors, nec |
| 11 | 13.2 | Banca Antonveneta SpA | Italy | Banca Monte dei Paschi di Siena SpA | Italy | Banks |
| 12 | 10.5 | Alcon Inc | United States | Novartis AG | Switzerland | Pharmaceutical preparations |
| 13 | 10.3 | Dr Pepper Snapple Group Inc | United States | Shareholders | United States | Investors, nec |
| 14 | 8.9 | Vin & Sprit AB | Sweden | Pernod Ricard SA | France | Distilled and blended liquors |
| 15 | 8.8 | Barr Pharmaceuticals Inc | United States | Teva Pharmaceutical Industries Ltd | Israel | Pharmaceutical preparations |
| 16 | 8.7 | Millennium Pharmaceuticals Inc | United States | Mahogany Acquisition Corp | United States | Investors, nec |
| 17 | 8.6 | Commerce Bancorp Inc. | United States | Toronto-Dominion Bank | Canada | Banks |
| 18 | 8.0 | NAVTEQ Corp | United States | Nokia Oyj | Finland | Radio & TV broadcasting & communications equipment |
| 19 | 7.9 | Origin Energy Ltd-Coal Seam Gas Assets | Australia | ConocoPhillips Co | United States | Crude petroleum and natural gas |
| 20 | 7.8 | Morgan Stanley | United States | Mitsubishi UFJ Financial Group Inc | Japan | Banks |
| 21 | 7.8 | China Netcom Group Corp Ltd (Hong Kong) | Hong Kong, China | China Unicom Ltd | Hong Kong, China | Telephone communications, except radiotelephone |
| 22 | 7.0 | E.ON Sverige AB | Sweden | E.ON Scandinavia AB | Sweden | Electric services |
| 23 | 7.0 | Angel Trains Ltd | United Kingdom | Investor Group | Australia | Investors, nec |
| 24 | 6.6 | Citibank Privatkunden AG & Co KGaA | Germany | Banque Federative du Credit Mutuel | France | Banks |
| 25 | 6.6 | MidCon Corp | United States | Investor Group | Australia | Investors, nec |
| 26 | 6.5 | Vivendi Universal Games Inc | United States | Activision Inc | United States | Prepackaged Software |
| 27 | 6.1 | British Energy Group PLC | United Kingdom | Lake Acquisitions Ltd | United Kingdom | Investors, nec |
| 28 | 5.6 | APP Pharmaceuticals Inc | United States | Fresenius SE | Germany | Electromedical and electrotherapeutic apparatus |
| 29 | 5.6 | Standard Bank Group Ltd | South Africa | Industrial & Commercial Bank of China | China | Banks |
| 30 | 5.5 | Business Objects SA | United States | Systeme Anwendungen Produkte AG | Germany | Prepackaged software |
| 31 | 5.5 | National Starch & Chemical Co. | United States | Henkel AG & Co KGaA | Germany | Perfumes, cosmetics, and other toilet preparations |
| 32 | 5.5 | Duvernay Oil Corp | Canada | Shell Canada Ltd | Canada | Crude petroleum and natural gas |
| 33 | 5.3 | Respironics Inc | United States | Koninklijke Philips Electronics NV | Netherlands | Household audio and video equipment |
| 34 | 5.3 | LEG Landesentwicklungs gesellschaft NRW GmbH | Germany | Whitehall Street Real Estate Fund | United States | Investment offices, nec |
| 35 | 5.1 | DRS Technologies Inc | United States | Finmeccanica SpA | Italy | Search, detection, and navigation equipment |
| 36 | 5.0 | Cognos Inc | Canada | International Business Machines Corp | United States | Computer programming services |
| 37 | 4.9 | Prvni Privatizacni Fond AS | Czech Republic | Assicurazioni Generali SpA | Italy | Life insurance |
| 38 | 4.7 | Philadelphia Consolidated Holdings Corp | United States | Tokio Marine Holdings Inc | Japan | Fire, marine, and casualty insurance |
| 39 | 4.5 | Energy East Corp | United States | Iberdrola SA | Spain | Electric services |
| 40 | 4.5 | Nikko Cordial Corp | Japan | Citigroup Japan Holdings Ltd | Japan | Investors, nec |
| 41 | 4.4 | Merrill Lynch & Co Inc | United States | Temasek Holdings (Pte) Ltd | Singapore | Management investment offices, open-end |
| 42 | 4.4 | Scania AB | Sweden | Volkswagen AG | Germany | Motor vehicles and passenger car bodies |
| 43 | 4.3 | Steen & Strom ASA | Norway | Investor Group | France | Investors, nec |
| 44 | 4.2 | Distrigaz SA | Belgium | ENI G&P Belgium SpA | Belgium | Natural gas transmission and distribution |
| 45 | 4.1 | House of Prince A/S | Denmark | British American Tobacco PLC | United Kingdom | Cigarettes |
| 46 | 4.1 | Lafarge SA | France | NNS Holding | Egypt | Investors, nec |
| 47 | 4.1 | OMX AB | Sweden | Nasdaq Stock Market Inc | United States | Security and commodity exchanges |
| 48 | 4.1 | Hagemeyer NV | Netherlands | Kelium Acquisition Holding | Netherlands | Investors, nec |
| 49 | 4.1 | ConvaTec Ltd | United States | Cidron Healthcare Ltd | Jersey | Investors, nec |
| 50 | 4.0 | IPSCO Inc-Canadian Tubular Operations | Canada | Evraz Group SA | Russian Federation | Steel foundries, nec |
| 51 | 4.0 | Hellenic Telecommunications Organization SA | Greece | Deutsche Telekom AG | Germany | Telephone communications, except radiotelephone |
| 52 | 4.0 | PrimeWest Energy Trust | Canada | Abu Dhabi National Energy Co PJSC {TAQA} | United Arab Emirates | Crude petroleum and natural gas |
| 53 | 3.8 | ChoicePoint Inc | United States | Reed Elsevier Group PLC | United Kingdom | Periodicals: publishing, or publishing & printing |
| 54 | 3.7 | UnionBanCal Corp. | United States | Bank of Tokyo-Mitsubishi UFJ Ltd | Japan | Banks |
| 55 | 3.7 | Evonik Industries AG | Germany | CVC Capital Partners Ltd | Luxembourg | Investors, nec |
| 56 | 3.7 | Burren Energy PLC | United Kingdom | Eni UK Holding PLC | United Kingdom | Investors, nec |
| 57 | 3.7 | Ventana Medical Systems Inc | United States | Roche Holding AG | Switzerland | Pharmaceutical preparations |
| 58 | 3.6 | Fortis Banque Luxembourg SA | Luxembourg | Grand Duchy of Luxembourg | Luxembourg | National government |
| 59 | 3.6 | MGI PHARMA Inc | United States | Jaguar Acquisition Corp | United States | Investors, nec |
| 60 | 3.5 | IronX Mineracao SA | Brazil | Anglo American PLC | United Kingdom | Gold ores |
| 61 | 3.4 | Ranbaxy Laboratories Ltd | India | Daiichi Sankyo Co Ltd | Japan | Pharmaceutical preparations |
| 62 | 3.4 | OMX AB | Sweden | Dubai International Financial Centre | United Arab Emirates | Management investment offices, open-end |
| 63 | 3.4 | Chesapeake Energy Corp. | United States | StatoilHydro ASA | Norway | Crude petroleum and natural gas |
| 64 | 3.3 | Queensland Gas Co Ltd | Australia | BG Group PLC | United Kingdom | Crude petroleum and natural gas |
| 65 | 3.3 | Maxit Holding GmbH | Germany | Cie de Saint-Gobain SA | France | Glass products, made of purchased glass |
| 66 | 3.2 | Enel Viesgo SA | Spain | E.ON AG | Germany | Electric services |
| 67 | 3.2 | Corporate Express NV | Netherlands | Staples Inc | United States | Stationery stores |
| 68 | 3.2 | Banque de Savoie | France | Banque Federale des Banques Populaires SA | France | Banks |
| 69 | 3.2 | Territorial Generation Co No 10 {TGC-10} | Russian Federation | Fortum Oyj | Finland | Electric services |
| 70 | 3.2 | Xella International GmbH | Germany | Xella International GmbH SPV | France | Investors, nec |
| 71 | 3.1 | Nacionale Minerios SA | Brazil | Investor Group | Japan | Investors, nec |
| 72 | 3.1 | Tuas Power Ltd | Singapore | SinoSing Power Pte Ltd | Singapore | Electric services |
| 73 | 3.0 | SigmaKalon Group BV | Netherlands | PPG Industries Inc | United States | Paints, varnishes, lacquers, & allied products |